Population biology: Evolution of pesticide resistance

PESTICIDE RESISTANCE MANAGEMENT Pesticide Resistance Management

Analytical methods for detecting pesticide switches with evolution of pesticide resistance.

After a pest develops resistance to a pesticide, switching between different unrelated pesticides is a common management option, but this raises the following questions: (1) What is the optimal frequency of pesticide use? (2) How do the frequencies of pesticide applications affect the evolution of pesticide resistance? (3) How can the time when the pest population reaches the economic injury le...

Classification: Biological Sciences - Population Biology When does high-dose antimicrobial chemotherapy prevent the evolution of resistance?

High-dose chemotherapy has long been advocated as a means of controlling 1 drug resistance in infectious diseases but recent empirical and theoretical studies have 2 begun to challenge this view. We show how high-dose chemotherapy engenders opposing 3 evolutionary processes involving the mutational input of resistant strains and their release 4 from ecological competition. Whether such therapy ...

Molecular biology and evolution of resistance of toxicants.

To the prevailing biochemical/physiological classification of mechanisms of organismal resistance to toxicants, an additional molecular dimension is proposed. Predictions are developed regarding the relative prevalence of different classes of mutations and are found to compare favorably with reports from the literature. In particular, point mutations in target loci were the dominant form of res...

Antibiotic resistance shaping multi-level population biology of bacteria

Antibiotics have natural functions, mostly involving cell-to-cell signaling networks. The anthropogenic production of antibiotics, and its release in the microbiosphere results in a disturbance of these networks, antibiotic resistance tending to preserve its integrity. The cost of such adaptation is the emergence and dissemination of antibiotic resistance genes, and of all genetic and cellular ...